Complete Blood Count(CBC)

In this laboratory, we have two Coulter LH750 analysers to deal with the FBC test.

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CBC Definition:
Complete blood count or known as Full blood count (FBC), is a panel of tests that used to evaluate 3 types of blood cells.



WBC evaluation : infection, cancer, allergies, inflammation.

• WBC count - total no. of WBC
• WBC Differential - measure the no. of various types of WBC
• Neutrophils
• Eosinophils
• Basophils
• Lymphocytes
• Monocytes

• When the result for WBC differential is not shown on the analyser, it indicates that the patient's sample is either jaundice or lipidemic. 
• To solve the problem, the sample can be diluted and the test is redo once again.
  **Diluent 500μl+sample 500μl** . 
• The result for WBC, RBC, HGB, HCT and platelets should times 2.
• Sometimes, even the sample has been diluted but the differential result is not shown by the analyzer. To overcome this, I need to do the counting manually using microscope.

RBC evaluation

• RBC count - actual no. of RBC
• Hemoglobin - total no. of oxygen-bearing protein in the blood, generally reflects the RBC no.
• Hematocrit - measure the % of a person's total blood volume which containing RBC
• Physical characteristic of RBC:
• MCV
• MCH
• MCHC
• Red cell distribution width (RDW) - measure the variation in the RBC size.
• Reticulocyte count - measure the absolute count / percentage of young RBC.

Platelets evaluation

• Platelets count - no. of platelets
• Mean platelet volume (MPV) - measure the average size of platelets
• Platelet distribution width (PDW) - reflect uniformity of platelets in size. 

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More information about the Explanation of CBC result: